Microsphere Design and Development for Fluvastatin Sodium Sustained Release

Author(s)	P. Venkatesh, Dr. Gopinadh Vuyyala, Dr. D. Varun, Nimma Vijaya Rekha, S.K. Godasu
Country	India
Abstract	Microencapsulation is the process of turning liquids into solids, changing surface and colloidal features, protecting the environment, and regulating release characteristics by the use of coating materials. For individuals with stable angina pectoris who are not well managed or who are intolerant of first-line treatments, is recommended as a symptomatic therapy. The study's goal is to create Fluvastatin Sodium double-walled microspheres utilizing various polymers and the solvent evaporation technique. In the current study, doubly walled microspheres of fluvastatin sodium were designed to be administered orally using sodium alginate, carbopol 934, HPMC K100, and guar gum as copolymers. When compared to other plans, F7 displays the maximum drug discharge in 12 hours. An analysis of the pharmaceutical discharge system revealed that it adhered to zero request kinetics and the non-fickian dissemination instrument. The definition coded F7 was closed as the best strategy due to the implications of the evaluation tests.
Keywords	Fluvastatin Sodium, Sustained release microspheres, Formulation, Evaluation.
Field	Medical / Pharmacy
Published In	Volume 17, Issue 1, January-June 2026
Published On	2026-06-09
DOI	https://doi.org/10.71097/IJAIDR.v17.i1.1995
Short DOI	https://doi.org/hb7437

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